Anti-Sorbitol Dehydrogenase抗体(ab123497)

概述

  • 产品名称Anti-Sorbitol Dehydrogenase抗体
    参阅全部 Sorbitol Dehydrogenase 一抗
  • 描述
    兔多克隆抗体to Sorbitol Dehydrogenase
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Sheep, Rabbit, Cow, Dog, Pig, Chimpanzee, Ferret, Rhesus monkey, Orangutan, Bat
  • 免疫原

    Synthetic peptide, corresponding to a region within the N terminal amino acids 1-50 of Human Sorbitol Dehydrogenase using the numbering given in entry NP_003095.2.

  • 阳性对照
    • HeLa whole cell lysate

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab123497 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-10 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm.
    • 组织特异性Expressed in kidney and epithelial cells of both benign and malignant prostate tissue. Expressed in epididymis (at protein level).
    • 序列相似性Belongs to the zinc-containing alcohol dehydrogenase family.
    • 细胞定位Mitochondrion membrane. Cell projection > cilium > flagellum. Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DHSO_HUMAN antibody
      • L iditol 2 dehydrogenase antibody
      • L-iditol 2-dehydrogenase antibody
      • OTTHUMP00000161939 antibody
      • SDH antibody
      • Sorbitol dehydrogenase 1 antibody
      • Sorbitol dehydrogenase antibody
      • SORD 1 antibody
      • SORD antibody
      • SORD1 antibody
      see all

    Anti-Sorbitol Dehydrogenase antibody 图像

    • Immunoprecipitation from HeLa whole cell lysate (1 mg for IP, 20% of IP loaded), using ab123497 at 6 µg/mg lysate for IP.
      Subsequent Western blot detection used an antibody which recognized an downstream epitope of Sorbitol Dehydrogenase at 0.4 µg/ml.
      Detection: Chemiluminescence with an exposure time of 10 seconds

    Anti-Sorbitol Dehydrogenase antibody (ab123497)参考文献

    ab123497 has not yet been referenced specifically in any publications.

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