Anti-Somatostatin Receptor 1抗体(ab100881)

概述

  • 产品名称
    Anti-Somatostatin Receptor 1抗体
    参阅全部 Somatostatin Receptor 1 一抗
  • 描述
    兔多克隆抗体to Somatostatin Receptor 1
  • 经测试应用
    适用于: WB, IHC-P, ICC, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat
    预测可用于: Horse, Cow, Dog, Human, Pig
  • 免疫原

    Synthetic peptide:

    ESGGVFRNGTCASRISTL

    , corresponding to C terminal amino acids 374-391 of Mouse and Rat Somatostatin Receptor 1

性能

应用

Our Abpromise guarantee covers the use of ab100881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/5000. Predicted molecular weight: 43 kDa.
IHC-P 1/2000.
ICC 1/5000.
ICC/IF Use at an assay dependent concentration.

靶标

  • 功能
    Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
  • 组织特异性
    Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • G-protein coupled receptor antibody
    • Somatostatin R1 antibody
    • Somatostatin receptor 1 antibody
    • Somatostatin receptor isoform 1 antibody
    • Somatostatin receptor type 1 antibody
    • SRIF 2 antibody
    • SRIF-2 antibody
    • SRIF2 antibody
    • SS-1-R antibody
    • SS1 R antibody
    • SS1-R antibody
    • SS1R antibody
    • SSR1_HUMAN antibody
    • SSTR 1 antibody
    • Sstr1 antibody
    see all

图片

  • ab100881 at 1/5000 showing dual labeling of anti-sst1 (green) and somatostatin (red). Anti-Sst1 shows sst1 in neuronal terminals co-localized with somatostatin
  • ab100881 showing anti-Sst1 depicts sst1 as a presynaptic receptor in the superficial layers of the spinal cord dorsal horn

文献

ab100881 has not yet been referenced specifically in any publications.

客户评价及客户问答

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Blocking step
nomal goat serum as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 20°C
Antigen retrieval step
None
Sample
Mouse Tissue sections (Brain)
Specification
Brain
Permeabilization
Yes - 0,3% Triton X100
Fixative
Paraformaldehyde
Username

Abcam user community

Verified customer

提交于 Nov 13 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册