生物素Anti-Soluble TNF Receptor II抗体(ab83158)
Key features and details
- Biotin Rabbit polyclonal to Soluble TNF Receptor II
- Suitable for: Sandwich ELISA, WB
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
概述
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产品名称
生物素Anti-Soluble TNF Receptor II抗体
参阅全部 Soluble TNF Receptor II 一抗 -
描述
生物素兔多克隆抗体to Soluble TNF Receptor II -
宿主
Rabbit -
偶联物
Biotin -
经测试应用
适用于: Sandwich ELISA, WBmore details -
种属反应性
与反应: Human -
免疫原
Highly pure (>98%) recombinant Human Soluble TNF Receptor II
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Centrifuge vial prior to opening. Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab83158 is sterile filtered. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Isotype control
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Recombinant Protein
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sELISA pair antibody
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab83158于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Sandwich ELISA |
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit polyclonal to Soluble TNF Receptor II (ab109853).
Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human Soluble TNF Receptor II. |
|
WB |
Use at an assay dependent concentration.
|
说明 |
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Sandwich ELISA
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit polyclonal to Soluble TNF Receptor II (ab109853). Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human Soluble TNF Receptor II. |
WB
Use at an assay dependent concentration. |
靶标
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功能
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. -
序列相似性
Contains 4 TNFR-Cys repeats. -
翻译后修饰
Phosphorylated; mainly on serine residues and with a very low level on threonine residues.
A soluble form (tumor necrosis factor binding protein 2) is produced from the membrane form by proteolytic processing. -
细胞定位
Secreted and Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 7133 Human
- Omim: 191191 Human
- SwissProt: P20333 Human
- Unigene: 256278 Human
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别名
- CD120b antibody
- p75 antibody
- p75 TNF receptor antibody
see all
数据表及文件
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Datasheet download
文献 (0)
ab83158 尚未被引用在任何文献中。