Anti-Sodium Iodide Symporter抗体(ab83816)

概述

  • 产品名称
    Anti-Sodium Iodide Symporter抗体
    参阅全部 Sodium Iodide Symporter 一抗
  • 描述
    兔多克隆抗体to Sodium Iodide Symporter
  • 经测试应用
    适用于: WB, ICC/IF, IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 468 - 517 (PSEQTMRVLP SSAARCVALS VNASGLLDPA LLPANDSSRA PSSGMDASRP) of Human Sodium Iodide Symporter (NP_000444)

  • 阳性对照
    • 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab83816 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 69 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ICC/IF Use at an assay dependent concentration. PubMed: 22719903
IHC-Fr Use at an assay dependent concentration. PubMed: 22719903
IHC-P Use at an assay dependent concentration. PubMed: 22719903

靶标

  • 功能
    Mediates iodide uptake in the thyroid gland.
  • 组织特异性
    Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.
  • 疾病相关
    Thyroid dyshormonogenesis 1
  • 序列相似性
    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Na(+)/I(-) cotransporter antibody
    • Na(+)/I(-) symporter antibody
    • Na+/I- cotransporter antibody
    • Na+/I-symporter antibody
    • NIS antibody
    • SC5A5_HUMAN antibody
    • Slc5a5 antibody
    • sodium iodide symporter antibody
    • Sodium-iodide symporter antibody
    • Sodium/iodide cotransporter antibody
    • Solute carrier family 5 (sodium iodide symporter) member 5 antibody
    • solute carrier family 5 (sodium/iodide cotransporter), member 5 antibody
    • Solute carrier family 5 member 5 antibody
    • TDH1 antibody
    see all

图片

  • Anti-Sodium Iodide Symporter antibody (ab83816) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 69 kDa
    Observed band size : 69 kDa

文献

This product has been referenced in:
  • Zhang M  et al. Molecular In Vivo Imaging Using a Noninvasive Cardiac-Specific MLC-2v Promoter Driven Dual-Gene Recombinant Lentivirus Monitoring System. PLoS One 10:e0133952 (2015). IHC . Read more (PubMed: 26230833) »
  • Liu F  et al. Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex. PLoS One 7:e38589 (2012). ICC/IF, IHC-P, IHC-Fr ; Human . Read more (PubMed: 22719903) »

See all 2 Publications for this product

客户评价及客户问答

Thank you for your enquiry.

I am sorry to confirm that discount codes for the Abtrial testing in new applications and species needs to be given out before the customer purchases. Therefore, we are regrettably not able to provide a code in th...

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Thank you for your email. Apologies for the delay, but my colleague Miia is currently out of the office. Both ab17795 and ab83816 have been generated using peptides that would be unglycosylated, therefore they should recognize deglycosylated fragmen...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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