The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Detects a band of approximately 84 kDa (predicted molecular weight: 93 kDa).
功能Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
序列相似性Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
翻译后修饰Phosphorylated by PKA, which inhibits activity.
细胞定位Membrane. In intestinal epithelial cells, localizes to the ileal brush border.