Anti-Sodium / Hydrogen Exchanger 1抗体(ab67314)


  • 产品名称Anti-Sodium / Hydrogen Exchanger 1抗体
    参阅全部 Sodium / Hydrogen Exchanger 1 一抗
  • 描述
    兔多克隆抗体to Sodium / Hydrogen Exchanger 1
  • 经测试应用适用于: ICC/IF, WB, IHC-FoFr, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A 17 amino acid synthetic peptide from near the center of Human Sodium/ Hydrogen Exchanger 1.

  • 阳性对照
    • MOLT4 cell lysate. Human brain tissue.



Our Abpromise guarantee covers the use of ab67314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration. PubMed: 20817726
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 91 kDa (predicted molecular weight: 91 kDa).
IHC-FoFr Use at an assay dependent concentration. PubMed: 20712402
IHC-P Use at an assay dependent concentration.


  • 功能Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
  • 组织特异性Kidney and intestine.
  • 序列相似性Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • amiloride-sensitive antibody
    • APNH antibody
    • APNH1 antibody
    • FLJ42224 antibody
    • Na Li countertransporter antibody
    • Na(+)/H(+) antiporter antibody
    • Na(+)/H(+) exchanger 1 antibody
    • Na+ H+ antiporter amiloride-sensitive antibody
    • Na+ H+ antiporter antibody
    • Na+ H+ exchanger 1 antibody
    • NHE-1 antibody
    • NHE1 antibody
    • OTTHUMP00000004468 antibody
    • SL9A1_HUMAN antibody
    • SLC9A1 antibody
    • Sodium hydrogen exchanger 1 antibody
    • Sodium/hydrogen exchanger 1 antibody
    • solute carrier family 9 antibody
    • Solute carrier family 9 member 1 antibody
    • Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive antibody
    • Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1 antibody
    • Solute carrier family 9 subfamily A member 1 antibody
    see all

Anti-Sodium / Hydrogen Exchanger 1 antibody 图像

  • Lane 1 : Anti-Sodium / Hydrogen Exchanger 1 antibody (ab67314) at 1 µg/ml
    Lane 2 : Anti-Sodium / Hydrogen Exchanger 1 antibody (ab67314) at 2 µg/ml

    Lane 1 : MOLT4 cell lysate
    Lane 2 : MOLT4 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size : 91 kDa
    Observed band size : 91 kDa
    Additional bands at : 48 kDa (possible isoform).
  • Immunofluorescence of Nhe-1 in Human Brain cells using ab67314 at 20 ug/ml.

Anti-Sodium / Hydrogen Exchanger 1 antibody (ab67314)参考文献

This product has been referenced in:
  • Cengiz P  et al. Inhibition of Na+/H+ exchanger isoform 1 is neuroprotective in neonatal hypoxic ischemic brain injury. Antioxid Redox Signal 14:1803-13 (2011). WB, IHC-FoFr ; Mouse . Read more (PubMed: 20712402) »
  • Magalhaes MA  et al. Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. J Cell Biol 195:903-20 (2011). Read more (PubMed: 22105349) »

See all 3 Publications for this product

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