Anti-SOCS6抗体, prediluted (ab53211)

概述

  • 产品名称
    Anti-SOCS6抗体, prediluted
    参阅全部 SOCS6 一抗
  • 描述
    兔多克隆抗体to SOCS6, prediluted
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to C terminal of human SOCS6 protein.

  • 阳性对照
    • A431 and HeLa cells. Placenta.

性能

应用

Our Abpromise guarantee covers the use of ab53211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: Ready-to-use for 30 min at RT.

    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM
    citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
    • 通路
      Protein modification; protein ubiquitination.
    • 序列相似性
      Contains 1 SH2 domain.
      Contains 1 SOCS box domain.
    • 结构域
      The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CIS-4 antibody
      • CIS4 antibody
      • Cish4 antibody
      • Cytokine inducible SH2 protein 4 antibody
      • Cytokine-inducible SH2 protein 4 antibody
      • HSPC060 antibody
      • SOCS-4 antibody
      • SOCS-6 antibody
      • SOCS4 antibody
      • Socs6 antibody
      • SOCS6_HUMAN antibody
      • SSI4 antibody
      • STAI4 antibody
      • STAT induced STAT inhibitor 4 antibody
      • STAT4 antibody
      • STATI4 antibody
      • Suppressor of cytokine signaling 4 antibody
      • Suppressor of cytokine signaling 6 antibody
      see all

    文献

    This product has been referenced in:
    • Letellier E  et al. Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer. Br J Cancer 111:726-35 (2014). IHC-P ; Human . Read more (PubMed: 25025962) »

    See 1 Publication for this product

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