概述

  • 产品名称Anti-SOCS6抗体
    参阅全部 SOCS6 一抗
  • 描述
    小鼠单克隆抗体to SOCS6
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-536 of Human SOCS6

性能

应用

Our Abpromise guarantee covers the use of ab56516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
    • 通路Protein modification; protein ubiquitination.
    • 序列相似性Contains 1 SH2 domain.
      Contains 1 SOCS box domain.
    • 结构域The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CIS-4 antibody
      • CIS4 antibody
      • Cish4 antibody
      • Cytokine inducible SH2 protein 4 antibody
      • Cytokine-inducible SH2 protein 4 antibody
      • HSPC060 antibody
      • SOCS-4 antibody
      • SOCS-6 antibody
      • SOCS4 antibody
      • Socs6 antibody
      • SOCS6_HUMAN antibody
      • SSI4 antibody
      • STAI4 antibody
      • STAT induced STAT inhibitor 4 antibody
      • STAT4 antibody
      • STATI4 antibody
      • Suppressor of cytokine signaling 4 antibody
      • Suppressor of cytokine signaling 6 antibody
      see all

    Anti-SOCS6 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab56516 SOCS6 antibody at 1ug/ml. Predicted band size of immunogen is 85 kDa

    Anti-SOCS6 antibody (ab56516)参考文献

    ab56516 has not yet been referenced specifically in any publications.

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