, corresponding to C terminal amino acids 452-465 of Human SNX8.
Jurkat and Human Liver extracts.
GenBank Accession Number – NP_037453.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris-saline. pH 7.3
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Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 4 - 8 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network.
Belongs to the sorting nexin family.
Contains 1 PX (phox homology) domain.
Early endosome membrane. Colocalizes with retromer components.
Information by UniProt
Highly similar to MVP1 PROTEIN Saccharomyces cerevisiae antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SNX8 antibody (ab5988)
ab5988 (4µg/ml) staining of paraffin embedded Human Kidney following steamed antigen retrieval with Tris/EDTA buffer pH 9 and HRP-staining shows vesicular staining in the cytoplasm of preferentially DCT epithelial cells.
has not yet been referenced specifically in any publications.
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