概述

  • 产品名称
    Anti-SNX19抗体
  • 描述
    兔多克隆抗体to SNX19
  • 经测试应用
    适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen, corresponding to amino acids 625-750 of Human SNX19.

  • 阳性对照
    • Human kidney tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab121401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Perform Heat Induced Epitope Retrieval (HIER) at pH 6 using a pressure boiler as heat source.

靶标

  • 功能
    May be involved in several stages of intracellular trafficking.
  • 序列相似性
    Belongs to the sorting nexin family.
    Contains 1 PX (phox homology) domain.
    Contains 1 PXA domain.
  • 结构域
    The PX domain mediates specific binding to membranes enriched in phosphatidylinositol-3-phosphate (PtdIns(P3)).
  • 细胞定位
    Cytoplasmic vesicle membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • SNX19 antibody
    • SNX19_HUMAN antibody
    • Sorting nexin 19 antibody
    • Sorting nexin-19 antibody

图片

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in mitochondria. Recommended concentration of ab121401 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab121401 at 1/75 dilution staining SNX19 in Paraffin-embedded Human Kidney tissue by Immunohistochemistry.
    Note: strong cytoplasmic positivity in cells in tubules.

文献

ab121401 has not yet been referenced specifically in any publications.

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