Anti-SNX18抗体(ab96843)
Key features and details
- Rabbit polyclonal to SNX18
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SNX18抗体 -
描述
兔多克隆抗体to SNX18 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide, corresponding to a sequence within amino acids 566-628 (PLWVSESYST GEEASRDVDA WVFSLECKLD CSTGSFLLEY LALGNEYSFS KVQRVPLMTV LSF) of Human SNX18 (NP_443102).
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阳性对照
- H1299 and HeLa whole cell lysate (ab150035); 293T, HepG2, MOLT4 and Raji cell lysates.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96843于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 69 kDa.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 69 kDa. |
靶标
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功能
May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane. -
序列相似性
Belongs to the sorting nexin family.
Contains 1 BAR domain.
Contains 1 PX (phox homology) domain.
Contains 1 SH3 domain. -
结构域
The PX domain mediates interaction with membranes enriched in phosphatidylinositol-4,5-bisphosphate. -
细胞定位
Endomembrane system. Endosome membrane. Cell membrane. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation. - Information by UniProt
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数据库链接
- Entrez Gene: 112574 Human
- SwissProt: Q96RF0 Human
- Unigene: 432755 Human
- Unigene: 606166 Human
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别名
- FLJ11997 antibody
- FLJ32560 antibody
- FLJ61062 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab96843 尚未被引用在任何文献中。