概述

  • 产品名称Anti-SNX15抗体
    参阅全部 SNX15 一抗
  • 描述
    山羊多克隆抗体to SNX15
  • 特异性This antibody is expected to recognise both human isoforms.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    EEILRLHLSQLPP

    , corresponding to C terminal amino acids 330-342 of Human SNX15.

  • 阳性对照
    • 293 or human kidney cell lysate.
  • 常规说明Principal Names – SNX15; HSAF001435; sorting nexin 15; clone iota unknown protein Official Gene Symbol - SNX15 GenBank Accession Number – SNX15 LocusLink ID - 29907 (human) Gene Ontology terms - protein transporter activity; intracellular protein transport; intracellular signaling cascade; membrane; cytosol

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度IgG fraction
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab3990 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 1 µg/ml.

靶标

  • 功能May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN.
  • 组织特异性Widely expressed.
  • 序列相似性Belongs to the sorting nexin family.
    Contains 1 MIT domain.
    Contains 1 PX (phox homology) domain.
  • 结构域The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate.
  • 细胞定位Cytoplasm. Membrane. Cytoplasmic vesicle membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Clone iota unknown protein antibody
    • HSAF001435 antibody
    • SNX 15 antibody
    • SNX15 antibody
    • SNX15_HUMAN antibody
    • Sorting nexin 15 antibody
    • Sorting nexin-15 antibody
    see all

Anti-SNX15 antibody 图像

  • ab3990 staining (0.5µg/ml) of 293 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-SNX15 antibody (ab3990)参考文献

This product has been referenced in:
  • Danson C  et al. SNX15 links clathrin endocytosis to the PtdIns3P early endosome independently of the APPL1 endosome. J Cell Sci 126:4885-99 (2013). WB . Read more (PubMed: 23986476) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab3990.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"