概述

  • 产品名称
  • 描述
    山羊多克隆抗体to SNX15
  • 特异性
    This antibody is expected to recognise both human isoforms.
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    EEILRLHLSQLPP

    , corresponding to C terminal amino acids 330-342 of Human SNX15.

  • 阳性对照
    • 293 or human kidney cell lysate.
  • 常规说明
    Principal Names – SNX15; HSAF001435; sorting nexin 15; clone iota unknown protein Official Gene Symbol - SNX15 GenBank Accession Number – SNX15 LocusLink ID - 29907 (human) Gene Ontology terms - protein transporter activity; intracellular protein transport; intracellular signaling cascade; membrane; cytosol

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 纯化说明
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab3990 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 1 µg/ml.

靶标

  • 功能
    May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN.
  • 组织特异性
    Widely expressed.
  • 序列相似性
    Belongs to the sorting nexin family.
    Contains 1 MIT domain.
    Contains 1 PX (phox homology) domain.
  • 结构域
    The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate.
  • 细胞定位
    Cytoplasm. Membrane. Cytoplasmic vesicle membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Clone iota unknown protein antibody
    • HSAF001435 antibody
    • SNX 15 antibody
    • SNX15 antibody
    • SNX15_HUMAN antibody
    • Sorting nexin 15 antibody
    • Sorting nexin-15 antibody
    see all

Anti-SNX15 antibody 图像

  • ab3990 staining (0.5µg/ml) of 293 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

实验方案

Anti-SNX15 antibody (ab3990)参考文献

This product has been referenced in:
  • Danson C  et al. SNX15 links clathrin endocytosis to the PtdIns3P early endosome independently of the APPL1 endosome. J Cell Sci 126:4885-99 (2013). WB . Read more (PubMed: 23986476) »

See 1 Publication for this product

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