概述

  • 产品名称Anti-SNX1抗体
    参阅全部 SNX1 一抗
  • 描述
    小鼠单克隆抗体to SNX1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 166-276 of Human SNX1

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab55776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May be involved in several stages of intracellular trafficking. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
    • 序列相似性Belongs to the sorting nexin family.
      Contains 1 BAR domain.
      Contains 1 PX (phox homology) domain.
    • 细胞定位Endosome membrane. Golgi apparatus > trans-Golgi network membrane. Early endosome membrane. Enriched on tubular elements of the early endosome membrane. Binds preferentially to highly curved membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIn.
    • Information by UniProt
    • 数据库链接
    • 别名
      • HsT17379 antibody
      • MGC8664 antibody
      • SNX 1 antibody
      • SNX 1a antibody
      • Snx1 antibody
      • SNX1_HUMAN antibody
      • SNX1A antibody
      • Sorting nexin 1 antibody
      • Sorting nexin 1A antibody
      • Sorting nexin-1 antibody
      • Vps5 antibody
      see all

    Anti-SNX1 antibody 图像

    • SNX1 antibody (ab55776) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.


    • Predicted band size : 59 kDa
      SNX1 antibody (ab55776) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-SNX1 antibody (ab55776)参考文献

    ab55776 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"