概述

  • 产品名称Anti-SNRPD3抗体
    参阅全部 SNRPD3 一抗
  • 描述
    兔多克隆抗体to SNRPD3
  • 经测试应用适用于: IHC-P, WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Xenopus laevis
  • 免疫原

    Recombinant fragment, corresponding to amino acids 8-121 of Human SNRPD3 (P62318).

  • 阳性对照
    • RT4, U-251 MG and Human Tonsil cell lysates, Human small intestine tissue

性能

应用

Our Abpromise guarantee covers the use of ab121129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200.
WB 1/100 - 1/250.
ICC/IF Use at an assay dependent concentration.

靶标

  • 功能Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
  • 序列相似性Belongs to the snRNP core protein family.
  • 翻译后修饰Methylated on arginine residues by PRMT5 and PRMT7; methylation is required for assembly and biogenesis of snRNPs.
    Arg-97 is dimethylated, probably to asymmetric dimethylarginine.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Sm D3 antibody
    • Sm-D3 antibody
    • small nuclear ribonucleoprotein D3 polypeptide 18kDa antibody
    • Small nuclear ribonucleoprotein Sm D3 antibody
    • SmD3 antibody
    • SMD3_HUMAN antibody
    • snRNP core protein D3 antibody
    • SNRPD3 antibody
    see all

Anti-SNRPD3 antibody 图像

  • Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but excluded from the nucleoli.
  • All lanes : Anti-SNRPD3 antibody (ab121129) at 1/250 dilution

    Lane 1 : RT4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate

    Developed using the ECL technique
  • ab121129 staining SNRPD3 in Paraffin-emebedded Human small intestine tissue by Immunohistochemistry. Note: strong nuclear positivity in glandular cells.

Anti-SNRPD3 antibody (ab121129)参考文献

ab121129 has not yet been referenced specifically in any publications.

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