This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

概述

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, 0.5mg/ml Tris-saline. pH 7.3
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

  • 应用说明
    Peptide ELISA: antibody detection limit dilution 1/16000.
    WB: preliminary experiments give no signal but low background in human brain and testis lysates at up to 1µg/ml (note whole-cell RIPA lysates not nuclear lysates).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.
    • 组织特异性
      Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle.
    • 序列相似性
      Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
    • 细胞定位
      Nucleus. In some cells it may be found in typically 1 or 2 discrete nuclear aggregates of unknown function which also contain TP53BP1. Also found in multiple discrete nuclear foci which increase in number following treatment with ionizing radiation or interstrand cross-linking agents. These foci overlap with those formed by the MRN complex (composed of MRE11A, RAD50 and NBN) and BRCA1.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Dclre1a antibody
      • DCR1A_HUMAN antibody
      • DNA cross link repair 1A antibody
      • DNA cross link repair gene SNM1 antibody
      • DNA cross-link repair 1A protein antibody
      • hSNM1 antibody
      • hSNM1A antibody
      • PSO2 antibody
      • SNM1 homolog A antibody
      see all

    Anti-SNM1A antibody (ab14805)参考文献

    ab14805 has not yet been referenced specifically in any publications.

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