Anti-SNAP25抗体[SP12] (ab11102)

概述

  • 产品名称Anti-SNAP25抗体[SP12]
    参阅全部 SNAP25 一抗
  • 描述
    小鼠单克隆抗体[SP12] to SNAP25
  • 经测试应用适用于: IHC-P, ELISA, WBmore details
  • 种属反应性
    与反应: Rat, Hamster, Human, Pig
  • 免疫原

    Crude synaptic immunoprecipitate (Human).

  • 阳性对照
    • Brain.
  • 常规说明This product should be stored undiluted. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch.

性能

应用

Our Abpromise guarantee covers the use of ab11102 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
ELISA
WB
  • 应用说明ELISA: Use at an assay dependent dilution.
    IHC-P: 1/2000 - 1/5000. This product does not require protein digestion pre-treatment or antigen retrieval using heat treatment prior to staining of paraffin sections.
    WB: 1/500 - 1/5000. Detects a band of approximately 26-27 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
    • 组织特异性Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
    • 序列相似性Belongs to the SNAP-25 family.
      Contains 2 t-SNARE coiled-coil homology domains.
    • 翻译后修饰Palmitoylated. Cys-85 appears to be the main site, and palmitoylation is required for membrane association.
    • 细胞定位Cytoplasm > perinuclear region. Cell membrane. Cell junction > synapse > synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region.
    • Information by UniProt
    • 数据库链接
    • 别名
      • bA416N4.2 antibody
      • Bdr antibody
      • CMS18 antibody
      • dJ1068F16.2 antibody
      • FLJ23079 antibody
      • HGNC:11132 antibody
      • MGC105414 antibody
      • MGC139754 antibody
      • Resistance to inhibitors of cholinesterase 4 homolog antibody
      • RIC 4 antibody
      • RIC4 antibody
      • SEC 9 antibody
      • SEC9 antibody
      • SNAP 25 antibody
      • SNAP antibody
      • SNAP-25 antibody
      • SNAP-25B antibody
      • SNAP25 antibody
      • SNP 25 antibody
      • SNP25 antibody
      • SNP25_HUMAN antibody
      • sp antibody
      • SUP antibody
      • Super protein antibody
      • Synaptosomal associated 25 kDa protein antibody
      • Synaptosomal associated protein antibody
      • Synaptosomal associated protein 25 antibody
      • Synaptosomal associated protein 25kDa antibody
      • Synaptosomal-associated 25 kDa protein antibody
      • Synaptosomal-associated protein 25 antibody
      • Synaptosomal-associated protein, 25-KD antibody
      see all

    Anti-SNAP25 antibody [SP12] (ab11102)参考文献

    ab11102 has not yet been referenced specifically in any publications.

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