概述

  • 产品名称Anti-SMUG1抗体
    参阅全部 SMUG1 一抗
  • 描述
    兔多克隆抗体to SMUG1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human, African Green Monkey
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from an internal sequence of Human SMUG1 (UniProt ID: Q53HV7).

  • 阳性对照
    • 293 and COS7 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: without Mg2+ and Ca2+
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab110518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 30 kDa.

靶标

  • 功能Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FDG antibody
    • HMUDG antibody
    • MGC104370 antibody
    • Single strand selective monofunctional uracil DNA glycosylase 1 antibody
    • Single strand selective monofunctional uracil DNA glycosylase antibody
    • Single-strand selective monofunctional uracil DNA glycosylase antibody
    • SMUG 1 antibody
    • Smug1 antibody
    • SMUG1 protein antibody
    • SMUG1_HUMAN antibody
    • UNG 3 antibody
    • UNG3 antibody
    see all

Anti-SMUG1 antibody 图像

  • All lanes : Anti-SMUG1 antibody (ab110518) at 1/500 dilution

    Lane 1 : 293 cell lysate
    Lane 2 : COS7 cell lysate
    Lane 3 : Immunizing peptide


    Predicted band size : 30 kDa

Anti-SMUG1 antibody (ab110518)参考文献

ab110518 has not yet been referenced specifically in any publications.

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