概述

  • 产品名称
    Anti-Smoothened抗体
    参阅全部 Smoothened 一抗
  • 描述
    山羊多克隆抗体to Smoothened
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    C-NLMDTELMDADSD

    , corresponding to C terminal amino acids 774-786 of Human Smoothened

  • 阳性对照
    • Human Bone Marrow lysate.

性能

应用

Our Abpromise guarantee covers the use of ab58574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明
    Peptide ELISA: antibody detection limit dilution 1/32000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 86 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
    • 序列相似性
      Belongs to the G-protein coupled receptor Fz/Smo family.
      Contains 1 FZ (frizzled) domain.
    • 细胞定位
      Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Frizzled family member 11 antibody
      • FZD11 antibody
      • Gx antibody
      • Gx protein antibody
      • Protein Gx antibody
      • SMO antibody
      • SMO_HUMAN antibody
      • SMOH antibody
      • Smoothened frizzled family receptor antibody
      • Smoothened homolog (Drosophila) antibody
      • Smoothened homolog antibody
      • Smoothened homolog precursor (SMO) (Gx protein) antibody
      • Smoothened seven transmembrane spanning receptor antibody
      see all

    Anti-Smoothened antibody 图像

    实验方案

    Anti-Smoothened antibody (ab58574)参考文献

    ab58574 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab58574.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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