概述

性能

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应用

Our Abpromise guarantee covers the use of ab58574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: antibody detection limit dilution 1/32000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 86 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
    • 序列相似性Belongs to the G-protein coupled receptor Fz/Smo family.
      Contains 1 FZ (frizzled) domain.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Frizzled family member 11 antibody
      • FZD11 antibody
      • Gx antibody
      • Gx protein antibody
      • Protein Gx antibody
      • SMO antibody
      • SMO_HUMAN antibody
      • SMOH antibody
      • Smoothened frizzled family receptor antibody
      • Smoothened homolog (Drosophila) antibody
      • Smoothened homolog antibody
      • Smoothened homolog precursor (SMO) (Gx protein) antibody
      • Smoothened seven transmembrane spanning receptor antibody
      see all

    Anti-Smoothened antibody 图像

    Anti-Smoothened antibody (ab58574)参考文献

    ab58574 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"