Anti-Smoothelin抗体[4A83] (ab21108)

概述

  • 产品名称Anti-Smoothelin抗体[4A83]
    参阅全部 Smoothelin 一抗
  • 描述
    小鼠单克隆抗体[4A83] to Smoothelin
  • 特异性Reacts with the 59kD and 100kD protein, corresponding to smoothelin A and B, respectively.
  • 经测试应用适用于: IHC-Fr, IHC-P, ICC, WBmore details
  • 种属反应性
    与反应: Chicken, Cat, Dog, Human, Pig, Monkey
    不与反应: Mouse, Rat, Hamster
  • 免疫原

    Full length protein (Human smoothelin).

性能

应用

Our Abpromise guarantee covers the use of ab21108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 102 kDa.

靶标

  • 功能Structural protein of the cytoskeleton.
  • 组织特异性Smooth muscle; contractile or vascular (for the long form).
  • 序列相似性Belongs to the smoothelin family.
    Contains 1 CH (calponin-homology) domain.
  • 细胞定位Cytoplasm > cytoskeleton. Exhibits a filamentous organization.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ35168 antibody
    • FLJ35365 antibody
    • FLJ35620 antibody
    • FLJ38597 antibody
    • Smoothelin antibody
    • SMSMO antibody
    • Smtn antibody
    • SMTN_HUMAN antibody
    see all

Anti-Smoothelin antibody [4A83] 图像

  • ab21108 staining human small intestine tissue sections by IHC-P.  The sample was formaldehyde fixed and subjected to a heat mediated antigen retrieval in EDTA prior to incubation with ab21108 (1/1600) for 16 minutes at 25°C.  Polymer detection was with DAB (no enhancement) and a hematoxylin counterstain.

    See Abreview

Anti-Smoothelin antibody [4A83] (ab21108)参考文献

This product has been referenced in:
  • Bockmeyer CL  et al. Arteriolar vascular smooth muscle cell differentiation in benign nephrosclerosis. Nephrol Dial Transplant 27:3493-501 (2012). Read more (PubMed: 22319217) »
  • Bockmeyer CL  et al. ADAMTS13--marker of contractile phenotype of arterial smooth muscle cells lost in benign nephrosclerosis. Nephrol Dial Transplant : (2010). Read more (PubMed: 20923926) »

See all 2 Publications for this product

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I apologize for the inconvenience with ab683, and as we discussed I would be happy to send a replacement or issue a credit or refund. Also, please keep me updated about any further information about ab21108.
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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (small intestine)
Specification small intestine
Fixative Formaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: EDTA
Permeabilization No
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Mr. Ronald Houston

Verified customer

提交于 Jan 31 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"