Anti-smooth muscle Actin抗体(ab125044)

概述

  • 产品名称
    Anti-smooth muscle Actin抗体
  • 描述
    兔多克隆抗体to smooth muscle Actin
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to N terminal amino acids of Human smooth muscle Actin.

  • 阳性对照
    • Human colon and small intestine tissues.
  • 常规说明
    The user must validate any other storage conditions.

性能

应用

Our Abpromise guarantee covers the use of ab125044 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100.

靶标

  • 功能
    Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
  • 疾病相关
    Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
  • 序列相似性
    Belongs to the actin family.
  • 细胞定位
    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • a actin antibody
    • Acta 2 antibody
    • ACTA_HUMAN antibody
    • ACTA2 antibody
    • ACTA2 protein antibody
    • Actin alpha 2 smooth muscle aorta antibody
    • Actin antibody
    • Actin aortic smooth muscle antibody
    • Actin vascular smooth muscle antibody
    • ACTSA antibody
    • ACTVS antibody
    • Alpha 2 actin antibody
    • Alpha actin 2 antibody
    • Alpha cardiac actin antibody
    • Alpha smooth muscle antibody
    • Alpha-actin-2 antibody
    • aortic smooth muscle antibody
    • ASMA antibody
    • Cell growth-inhibiting gene 46 protein antibody
    • Growth inhibiting gene 46 antibody
    see all

图片

  • ab125044, at 1/100, staining smooth muscle Actin in formalin fixed, paraffin embedded Human small intestine tissue by Immunohistochemistry.

文献

ab125044 has not yet been referenced specifically in any publications.

客户评价及客户问答

Application
Immunocytochemistry/ Immunofluorescence
Sample
Human Cell (differentiated iPSC)
Permeabilization
Yes - 0.25% Triton X-100 in PBS
Specification
differentiated iPSC
Blocking step
BSA as blocking agent for 30 minute(s) · Concentration: 1% · Temperature: 22°C
Fixative
Paraformaldehyde
Username

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提交于 Apr 13 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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