概述

  • 产品名称Anti-SMOC1抗体
    参阅全部 SMOC1 一抗
  • 描述
    兔多克隆抗体to SMOC1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 283-313 of Human SMOC1 (NP_071420.1, NP_001030024.1).

  • 阳性对照
    • Mouse NIH3T3 cell line lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab116529 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG

相关产品

应用

Our Abpromise guarantee covers the use of ab116529 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 48 kDa.

靶标

  • 功能Plays essential roles in both eye and limb development. Probale regulator of osteoblast differentiation.
  • 组织特异性Widely expressed in many tissues with a strongest signal in ovary. No expression in spleen.
  • 疾病相关Defects in SMOC1 are the cause of ophthalmoacromelic syndrome (OAS) [MIM:206920]. A rare disorder presenting with anophthalmia or microphthalmia and limb anomalies. Limb malformations include fused 4th and 5th metacarpals and short 5th finger in hands, and olygodactyly in foot (four toes). Most patients have bilateral anophthalmia/ microphthalmia, but unilateral abnormality is also noted. Other malformations are rare, but venous or vertebral anomaly was recognized each in single cases.
  • 序列相似性Contains 2 EF-hand domains.
    Contains 1 Kazal-like domain.
    Contains 2 thyroglobulin type-1 domains.
  • 翻译后修饰Glycosylated.
  • 细胞定位Secreted > extracellular space > extracellular matrix > basement membrane. In or around the basement membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Secreted modular calcium-binding protein 1 antibody
    • SMOC-1 antibody
    • SMOC1 antibody
    • SMOC1_HUMAN antibody
    • SPARC-related modular calcium-binding protein 1 antibody
    see all

Anti-SMOC1 antibody 图像

  • Anti-SMOC1 antibody (ab116529) at 1/100 dilution + Mouse NIH3T3 cell line lysate at 35 µg

    Predicted band size : 48 kDa

Anti-SMOC1 antibody (ab116529)参考文献

This product has been referenced in:

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab116529.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"