概述

  • 产品名称Anti-SMNDC1抗体
    参阅全部 SMNDC1 一抗
  • 描述
    小鼠多克隆抗体to SMNDC1
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Full length Human SMNDC1 (NP_005862.1).

  • 阳性对照
    • Human placenta lysate, PC-12 cell lysate, Raw 264.7 cell lysate, A-431 cell lysate, NIH/3T3 cell lysate, SMNDC1 transfected 293T cell lysate, HeLa cells

性能

应用

Our Abpromise guarantee covers the use of ab89131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能Necessary for spliceosome assembly. Overexpression causes apoptosis.
  • 组织特异性Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas.
  • 序列相似性Belongs to the SMN family.
    Contains 1 Tudor domain.
  • 细胞定位Nucleus speckle. Nucleus > Cajal body. Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 30 kDa splicing factor SMNrp antibody
    • MGC106917 antibody
    • MGC112663 antibody
    • SMN related protein antibody
    • SMN-related protein antibody
    • smndc1 antibody
    • SMNR antibody
    • SPF30 antibody
    • SPF30_HUMAN antibody
    • Splicing factor 30, survival of motor neuron-related antibody
    • Survival motor neuron domain containing 1 antibody
    • Survival motor neuron domain containing protein 1 antibody
    • Survival motor neuron domain-containing protein 1 antibody
    • Survival of motor neuron related splicing factor 30 antibody
    • Survival of motor neuron-related-splicing factor 30 antibody
    see all

Anti-SMNDC1 antibody 图像

  • Anti-SMNDC1 antibody (ab89131) at 1 µg/ml + Human placenta lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 27 kDa
  • Anti-SMNDC1 antibody (ab89131) at 1 µg/ml + PC-12 cell lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 27 kDa
  • Anti-SMNDC1 antibody (ab89131) at 1 µg/ml + Raw 264.7 cell lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 27 kDa
  • Anti-SMNDC1 antibody (ab89131) at 1 µg/ml + A-431 cell lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 27 kDa
  • Anti-SMNDC1 antibody (ab89131) at 1 µg/ml + NIH/3T3 cell lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 27 kDa
  • All lanes : Anti-SMNDC1 antibody (ab89131) at 1 µg/ml

    Lane 1 : SMNDC1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 27 kDa
    Observed band size : 26 kDa (why is the actual band size different from the predicted?)
  • ab89131 at 10 µg/ml staining SMNDC1 in HeLa cells by Immunofluorescence.

Anti-SMNDC1 antibody (ab89131)参考文献

ab89131 has not yet been referenced specifically in any publications.

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