概述

  • 产品名称Anti-Smek1抗体
    参阅全部 Smek1 一抗
  • 描述
    山羊多克隆抗体to Smek1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog, Xenopus laevis, Zebrafish, a wide range of other species
  • 免疫原

    Synthetic peptide:

    C-EQQRERQDNPKLD

    , corresponding to internal sequence amino acids 645-657 of Human Smek1

  • 阳性对照
    • Human pancreas lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab63968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明Peptide ELISA: antibody detection limit dilution : 1/16000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 95 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
    • 序列相似性Belongs to the SMEK family.
      Contains 1 WH1 domain.
    • 细胞定位Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. In interphase localized in the cytoplasm and in the nucleus (with higher levels). During metaphase located in pericentriolar regions.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLFL1 antibody
      • KIAA2010 antibody
      • MEK1 SUPPRESSOR 1 antibody
      • MSTP033 antibody
      • P4R3A_HUMAN antibody
      • PP4R3 ALPHA antibody
      • PP4R3A antibody
      • PPP4R3A antibody
      • PROTEIN PHOSPHATASE 4, REGULATORY SUBUNIT 3, ALPHA antibody
      • Serine/threonine-protein phosphatase 4 regulatory subunit 3A antibody
      • SMEK homolog 1 antibody
      • SMEK homolog 1, suppressor of mek1 (Dictyostelium) antibody
      • smek1 antibody
      • SMK1 antibody
      see all

    Anti-Smek1 antibody 图像

    Anti-Smek1 antibody (ab63968)参考文献

    ab63968 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"