概述

  • 产品名称Anti-SMAD5抗体
    参阅全部 SMAD5 一抗
  • 描述
    小鼠单克隆抗体to SMAD5
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: KPLDICEFPF GSKQKEVCIN PYHYKRVESP VLPPVLVPRH NEFNPQHSLL VQFRNLSHNE PHMPQNATFP DSFHQPNN, corresponding to amino acids 105-182 of Human SMAD5

性能

应用

Our Abpromise guarantee covers the use of ab55484 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 52 kDa.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the dwarfin/SMAD family.
    Contains 1 MH1 (MAD homology 1) domain.
    Contains 1 MH2 (MAD homology 2) domain.
  • 翻译后修饰Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase.
    Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1.
  • 细胞定位Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp781C1895 antibody
    • DKFZp781O1323 antibody
    • Dwfc antibody
    • hSmad5 antibody
    • JV5 1 antibody
    • JV5-1 antibody
    • MAD homolog 5 antibody
    • MAD, mothers against decapentaplegic homolog 5 antibody
    • MADH 5 antibody
    • MADH5 antibody
    • Mothers against decapentaplegic homolog 5 antibody
    • mothers against decapentaplegic, drosophila, homolog of, 5 antibody
    • Mothers against DPP homolog 5 antibody
    • MusMLP antibody
    • SMA and MAD related protein 5 antibody
    • SMAD 5 antibody
    • SMAD family member 5 antibody
    • SMAD, mothers against DPP homolog 5 antibody
    • Smad5 antibody
    • SMAD5_HUMAN antibody
    see all

Anti-SMAD5 antibody 图像



  • Predicted band size : 52 kDa
    SMAD5 antibody (ab55484) at 1ug/lane + HeLa cell lysate at 25ug/lane.
  • ab55484 at 10 ug/ml staining smad5 in human Hella cells by Immunocytochemistry/ Immunofluorescence.

Anti-SMAD5 antibody (ab55484)参考文献

ab55484 has not yet been referenced specifically in any publications.

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