RabMAb

Anti-Smad3 (phospho S423 + S425)抗体[EP823Y] (ab52903)

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ab52903 被引用在 51 文献中.

  • Chen JL  et al. Development of novel activin-targeted therapeutics. Mol Ther 23:434-44 (2015). PubMed: 25399825
  • Yousef H  et al. Systemic attenuation of the TGF-ß pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal. Oncotarget 6:11959-78 (2015). WB ; Mouse . PubMed: 26003168
  • Newton FG  et al. Coordinate post-transcriptional repression of Dpp-dependent transcription factors attenuates signal range during development. Development 142:3362-73 (2015). In situ hybridization ; Drosophila melanogaster . PubMed: 26293305
  • Budi EH  et al. The insulin response integrates increased TGF-ß signaling through Akt-induced enhancement of cell surface delivery of TGF-ß receptors. Sci Signal 8:ra96 (2015). WB ; Mouse . PubMed: 26420907
  • Nyström A  et al. Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms. EMBO Mol Med 7:1211-28 (2015). WB ; Human . PubMed: 26194911
  • Aspalter IM  et al. Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch. Nat Commun 6:7264 (2015). Mouse . PubMed: 26081042
  • Tobar N  et al. c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells. BMC Cancer 14:640 (2014). WB ; Human . PubMed: 25175743
  • Hayashi A  et al. Inflammatory suppressive effect of prostate cancer cells with prolonged exposure to transforming growth factor ß on macrophage-differentiated cells via downregulation of prostaglandin E2. Oncol Lett 8:1513-1518 (2014). WB ; Human . PubMed: 25202359
  • Casari A  et al. A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development. Dev Biol 396:81-93 (2014). PubMed: 25286120
  • Biswas T  et al. Attenuation of TGF-ß signaling supports tumor progression of a mesenchymal-like mammary tumor cell line in a syngeneic murine model. Cancer Lett 346:129-38 (2014). PubMed: 24368187
  • Zerr P  et al. Vitamin D receptor regulates TGF-ß signalling in systemic sclerosis. Ann Rheum Dis N/A:N/A (2014). Human . PubMed: 24448349
  • Sulkowski M  et al. Postsynaptic glutamate receptors regulate local BMP signaling at the Drosophila neuromuscular junction. Development 141:436-47 (2014). PubMed: 24353060
  • Savar A  et al. Loss of epithelial p53 and av integrin cooperate through Akt to induce squamous cell carcinoma yet prevent remodeling of the tumor microenvironment. Oncogene N/A:N/A (2014). WB ; Mouse . PubMed: 24469034
  • Duffy DJ  et al. GSK3 inhibitors regulate MYCN mRNA levels and reduce neuroblastoma cell viability through multiple mechanisms, including p53 and Wnt signaling. Mol Cancer Ther 13:454-67 (2014). PubMed: 24282277
  • Tobar N  et al. Soluble MMP-14 produced by bone marrow-derived stromal cells sheds epithelial endoglin modulating the migratory properties of human breast cancer cells. Carcinogenesis N/A:N/A (2014). Human . PubMed: 24618373
  • Ma X  et al. Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary. PLoS One 9:e90267 (2014). IHC . PubMed: 24658126
  • O'Reilly S  et al. Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-ß (TGF-ß) signaling promoting SMAD3 activation and fibrosis via Gremlin protein. J Biol Chem 289:9952-60 (2014). WB ; Human . PubMed: 24550394
  • Boudreau HE  et al. Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-ß-mediated migration of human lung and breast epithelial cells. Br J Cancer 110:2569-82 (2014). Human . PubMed: 24714748
  • Wartlick O  et al. Growth control by a moving morphogen gradient during Drosophila eye development. Development 141:1884-93 (2014). PubMed: 24757005
  • Suragani RN  et al. Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine ß-thalassemia. Blood 123:3864-72 (2014). IHC-P ; Mouse . PubMed: 24795345
  • Maimon I  et al. Without children is required for Stat-mediated zfh1 transcription and for germline stem cell differentiation. Development 141:2602-10 (2014). Drosophila melanogaster . PubMed: 24903753
  • Pan L  et al. Protein competition switches the function of COP9 from self-renewal to differentiation. Nature 514:233-6 (2014). PubMed: 25119050
  • Guo T  et al. Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity. Elife 3:e03245 (2014). ICC/IF ; Mouse . PubMed: 25161195
  • Xu MY  et al. Stat3 signaling activation crosslinking of TGF-ß1 in hepatic stellate cell exacerbates liver injury and fibrosis. Biochim Biophys Acta 1842:2237-45 (2014). PubMed: 25092172
  • Tang MK  et al. Promyelocytic leukemia (PML) protein plays important roles in regulating cell adhesion, morphology, proliferation and migration. PLoS One 8:e59477 (2013). ICC/IF ; Mouse . PubMed: 23555679
  • Soofi A  et al. Kielin/chordin-like protein attenuates both acute and chronic renal injury. J Am Soc Nephrol 24:897-905 (2013). WB ; Mouse . PubMed: 23539757
  • Beckwith EJ  et al. Circadian period integrates network information through activation of the BMP signaling pathway. PLoS Biol 11:e1001733 (2013). IHC (PFA fixed) ; Drosophila melanogaster . PubMed: 24339749
  • Meyer C  et al. Caveolin-1 abrogates TGF-ß mediated hepatocyte apoptosis. Cell Death Dis 4:e466 (2013). WB ; Mouse . PubMed: 23328673
  • Chu IM  et al. Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß. PLoS One 8:e61125 (2013). WB . PubMed: 23577196
  • Chatterjee S  et al. Junctional adhesion molecule-a regulates vascular endothelial growth factor receptor-2 signaling-dependent mouse corneal wound healing. PLoS One 8:e63674 (2013). IHC-Fr ; Mouse . PubMed: 23667656
  • Maddaluno L  et al. EndMT contributes to the onset and progression of cerebral cavernous malformations. Nature 498:492-6 (2013). PubMed: 23748444
  • Chai Z  et al. Genetic Deletion of Cell Division Autoantigen 1 Retards Diabetes-Associated Renal Injury. J Am Soc Nephrol N/A:N/A (2013). PubMed: 23929772
  • Dzieran J  et al. Comparative analysis of TGF-ß/Smad signaling dependent cytostasis in human hepatocellular carcinoma cell lines. PLoS One 8:e72252 (2013). WB . PubMed: 23991075
  • Kim SS  et al. Nifedipine Induces Periostin Expression in Gingival Fibroblasts through TGF-beta. J Dent Res 92:1022-8 (2013). PubMed: 24004653
  • Zhu JN  et al. Smad3 Inactivation and MiR-29b Upregulation Mediate the Effect of Carvedilol on Attenuating the Acute Myocardium Infarction-Induced Myocardial Fibrosis in Rat. PLoS One 8:e75557 (2013). WB ; Mouse . PubMed: 24086569
  • Prakoura N  et al. Epithelial calreticulin up-regulation promotes profibrotic responses and tubulointerstitial fibrosis development. Am J Pathol 183:1474-87 (2013). PubMed: 24035512
  • Winbanks CE  et al. The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass. J Cell Biol 203:345-57 (2013). PubMed: 24145169
  • Liu Y  et al. Transforming growth factor-ß (TGF-ß)-mediated connective tissue growth factor (CTGF) expression in hepatic stellate cells requires Stat3 signaling activation. J Biol Chem 288:30708-19 (2013). WB, ICC/IF ; Human . PubMed: 24005672
  • Ding ZY  et al. Transforming growth factor ß induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling. Cell Signal 25:1981-92 (2013). Human . PubMed: 23727026
  • Chiu CS  et al. Increased muscle force production and bone mineral density in ActRIIB-Fc-treated mature rodents. J Gerontol A Biol Sci Med Sci 68:1181-92 (2013). WB ; Mouse . PubMed: 23525481
  • Ables ET & Drummond-Barbosa D Cyclin E controls Drosophila female germline stem cell maintenance independently of its role in proliferation by modulating responsiveness to niche signals. Development 140:530-40 (2013). IHC ; Drosophila melanogaster . PubMed: 23293285
  • Akiyama T  et al. A large bioactive BMP ligand with distinct signaling properties is produced by alternative proconvertase processing. Sci Signal 5:ra28 (2012). IHC ; Drosophila melanogaster . PubMed: 22472650
  • Kim SH  et al. Smad3 and its phosphoisoforms are prognostic predictors of hepatocellular carcinoma after curative hepatectomy. Hepatobiliary Pancreat Dis Int 11:51-9 (2012). IHC ; Human . PubMed: 22251470
  • Zhang P  et al. Activation of Wnt11 by transforming growth factor-ß drives mesenchymal gene expression through non-canonical Wnt protein signaling in renal epithelial cells. J Biol Chem 287:21290-302 (2012). WB . PubMed: 22556418
  • Gardner A  et al. The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation. Am J Pathol 180:2293-308 (2012). PubMed: 22525462
  • Zieba A  et al. Intercellular variation in signaling through the TGF-ß pathway and its relation to cell density and cell cycle phase. Mol Cell Proteomics 11:M111.013482 (2012). PubMed: 22442258
  • Ding Z  et al. SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression. Nature 470:269-73 (2011). WB ; Mouse . PubMed: 21289624
  • Michaeloudes C  et al. TGF-ß regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 300:L295-304 (2011). WB ; Human . PubMed: 21131394
  • González AM  et al. Assessment of the protective effects of oral tocotrienols in arginine chronic-like pancreatitis. Am J Physiol Gastrointest Liver Physiol 301:G846-55 (2011). WB ; Rat . PubMed: 21852363
  • Dejima K  et al. Novel contact-dependent bone morphogenetic protein (BMP) signaling mediated by heparan sulfate proteoglycans. J Biol Chem 286:17103-11 (2011). WB ; Drosophila melanogaster . PubMed: 21454551
  • Cunningham MF  et al. S100A4 expression is increased in stricture fibroblasts from patients with fibrostenosing Crohn's disease and promotes intestinal fibroblast migration. Am J Physiol Gastrointest Liver Physiol 299:G457-66 (2010). WB ; Human . PubMed: 20489045

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