概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab8381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

常规信息

  • 别名
    • 0610041G12Rik
    • DBLOH_HUMAN
    • DBOH
    • DFNA64
    • diablo
    • Diablo homolog
    • Diablo homolog (Drosophila)
    • Diablo homolog mitochondrial
    • Diablo IAP binding mitochondrial protein
    • Diablo like protein
    • DIABLO S
    • Direct IAP binding protein with low pI
    • Direct IAP-binding protein with low pI
    • FLJ10537
    • FLJ25049
    • mitochondrial
    • Mitochondrial Smac protein
    • Second mitochondria derived activator of caspase
    • Second mitochondria-derived activator of caspase
    • Smac
    • SMAC 3
    • Smac protein
    • SMAC3
    see all
  • 功能Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP).
  • 组织特异性Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes.
  • 结构域The mature N-terminus mediates interaction with XIAP.
  • 细胞定位Mitochondrion. Released into the cytosol when cells undergo apoptosis.
  • Information by UniProt

Smac / Diablo peptide (ab8381)参考文献

ab8381 has not yet been referenced specifically in any publications.

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