概述

  • 产品名称Anti-SLURP1抗体
    参阅全部 SLURP1 一抗
  • 描述
    小鼠单克隆抗体to SLURP1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: CYTCKEPMTS ASCRTITRCK PEDTACMTTL VTVEAEYPFN QSPVVTRSCS SSCVATDPDS IGAAHLIFCC FRDLCNSE, corresponding to amino acids 25-103 of Human SLURP1

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab57569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性SLURP1 (Secreted LY6/PLAUR domain containing 1) belongs to the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. SLURP1 potentiates alpha-7 nicotinic acetylcholine receptors (CHRNA7) in keratinocytes and is implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. It is a marker of late differentiation of the skin and has an antitumor activity. Mutations in the SLURP1 gene are the cause of Mal de Meleda (MDM), a rare autosomal recessive genetic disease, characterized by inflammatory palmoplantar keratoderma.
    • 细胞定位Secreted
    • 数据库链接
    • 别名
      • Anti neoplastic urinary protein antibody
      • ANUP antibody
      • ARS antibody
      • ARS component B antibody
      • ARS(component B) 81/S antibody
      • ArsB antibody
      • LY6LS antibody
      • Lymphocyte antigen 6 like secreted antibody
      • MDM antibody
      • Results in cobblestone changes in the skin of the palm antibody
      • Secreted Ly 6/uPAR related protein 1 antibody
      • Secreted LY6/PLAUR domain containing 1 antibody
      • Secreted Ly6/uPAR related protein 1 antibody
      • SLURP 1 antibody
      see all

    Anti-SLURP1 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57569 SLURP1 antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    Anti-SLURP1 antibody (ab57569)参考文献

    This product has been referenced in:
    • Gay M  et al. Proteomic Analysis of Polypeptides Captured from Blood during Extracorporeal Albumin Dialysis in Patients with Cholestasis and Resistant Pruritus. PLoS One 6:e21850 (2011). WB ; Human . Read more (PubMed: 21779339) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"