概述

  • 产品名称Anti-SLITRK5抗体
    参阅全部 SLITRK5 一抗
  • 描述
    兔多克隆抗体to SLITRK5
  • 特异性ab67309 is predicted to have no cross-reactivity to other SLITRK proteins.
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A 14 amino acid synthetic peptide from near the center of human SLITRK5.

  • 阳性对照
    • 3T3 cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab67309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 160 kDa (predicted molecular weight: 107 kDa).
ICC/IF Use a concentration of 20 µg/ml.

靶标

  • 相关性SLIT and NTRK-like family 5 (SLITRK5) is a member a protein family consisting of six homologous transmembrane proteins (SLITRK1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of SLITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other SLITRK protein except SLITRK1, overexpression of SLITRK5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
  • 细胞定位Membrane; Single-pass type I membrane protein.
  • 数据库链接
  • 别名
    • bA364G4.2 antibody
    • KIAA0918 antibody
    • Leucine rich repeat containing 11 antibody
    • Leucine rich repeat containing protein 11 antibody
    • LRRC 11 antibody
    • LRRC11 antibody
    • SLIT and NTRK like family member 5 antibody
    • SLIT and NTRK like protein 5 antibody
    • Slit and trk like gene 5 antibody
    • SLITRK 5 antibody
    see all

Anti-SLITRK5 antibody 图像

  • All lanes : Anti-SLITRK5 antibody (ab67309) at 1 µg/ml

    Lane 1 : 3T3 cell lysate with no blocking peptide
    Lane 2 : 3T3 cell lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 107 kDa
    Observed band size : 160 kDa (why is the actual band size different from the predicted?)
  • Immunofluorescence of SLITRK5 in Human Brain cells using ab67309 at 5 µg/ml.

Anti-SLITRK5 antibody (ab67309)参考文献

This product has been referenced in:
  • Kogan-Sakin I  et al. Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells. Cell Death Differ : (2010). Read more (PubMed: 20689556) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"