概述

  • 产品名称
  • 描述
    兔多克隆抗体to Slit3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Cow
    预测可用于: Mouse, Rat, Chicken, Human
  • 免疫原

    Synthetic peptide:

    GKDSYVELASAKVR-C

    conjugated to KLH, corresponding to amino acids 1164-1177 of Human Slit3.

  • 常规说明
    Expiration date is 1 year from date of opening.

性能

应用

Our Abpromise guarantee covers the use of ab11018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Detects a band of approximately 145 kDa (predicted molecular weight: 169 kDa).

靶标

  • 功能
    May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
  • 组织特异性
    Predominantly expressed in thyroid.
  • 序列相似性
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
    Contains 9 EGF-like domains.
    Contains 1 laminin G-like domain.
    Contains 20 LRR (leucine-rich) repeats.
    Contains 4 LRRCT domains.
    Contains 4 LRRNT domains.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ10764 antibody
    • KIAA0814 antibody
    • MEGF 5 antibody
    • MEGF5 antibody
    • Multiple EGF-like domains protein 5 antibody
    • Multiple epidermal growth factor like domains 5 antibody
    • Multiple epidermal growth factor-like domains protein 5 antibody
    • SLIL 2 antibody
    • SLIL2 antibody
    • SLIT 1 antibody
    • Slit 2 antibody
    • Slit 3 antibody
    • Slit homolog 3 (Drosophila) antibody
    • Slit homolog 3 antibody
    • Slit homolog 3 protein antibody
    • Slit-3 antibody
    • SLIT1 antibody
    • Slit2 antibody
    • Slit3 antibody
    • SLIT3_HUMAN antibody
    see all

图片

  • Anti-Slit3 antibody (ab11018) at 1/800 dilution + Bovine thyroid whole cell lysate at 35 µg

    Secondary
    Goat-anti-Rabbit IgG [H&L] at 1/10000 dilution

    Predicted band size : 169 kDa
    Observed band size : 145 kDa (why is the actual band size different from the predicted?)

实验方案

文献

This product has been referenced in:
  • Pi L  et al. CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators. FASEB J : (2012). WB . Read more (PubMed: 22611085) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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