概述

  • 产品名称Anti-SLIRP抗体
    参阅全部 SLIRP 一抗
  • 描述
    兔多克隆抗体to SLIRP
  • 经测试应用适用于: IHC-Fr, WBmore details
  • 种属反应性
    与反应: Human
    不与反应: Mouse
  • 免疫原

    Synthetic peptide made to a C terminal region of human SLIRP.

  • 阳性对照
    • Human liver lysate

性能

应用

Our Abpromise guarantee covers the use of ab51523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 12 kDa (predicted molecular weight: 12 kDa).

靶标

  • 相关性SLIRP is a RNA binding protein that acts as a nuclear receptor corepressor. It may act by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. SLIRP binds the STR7 loop of SRA RNA. It is also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation. It contains 1 RRM (RNA recognition motif) domain. SLIRP is predominantly founs in mitochondrial with a limited role in the nucleus where it is recruited to nuclear receptor target promoters.
  • 细胞定位Mitochondrial and Nuclear; Predominantly mitochondrial.
  • 数据库链接
  • 别名
    • C14orf156 antibody
    • Chromosome 14 open reading frame 156 antibody
    • DC50 antibody
    • PD04872 antibody
    • SLIRP antibody
    • SRA stem loop interacting RNA binding protein, mitochondrial antibody
    see all

Anti-SLIRP antibody 图像

  • Anti-SLIRP antibody (ab51523) at 0.6 µg/ml + human liver lysate

    Predicted band size : 12 kDa
    Observed band size : 12 kDa

Anti-SLIRP antibody (ab51523)参考文献

This product has been referenced in:
  • Carpp LN  et al. Quantitative proteomic analysis of host-virus interactions reveals a role for Golgi brefeldin A resistance factor 1 (GBF1) in dengue infection. Mol Cell Proteomics 13:2836-54 (2014). Read more (PubMed: 24855065) »
  • Clemente P  et al. hCOA3 stabilizes cytochrome c oxidase 1 (COX1) and promotes cytochrome c oxidase assembly in human mitochondria. J Biol Chem 288:8321-31 (2013). Read more (PubMed: 23362268) »

See all 6 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Human Tissue sections (Normal skeletal muscle)
Specification Normal skeletal muscle
Fixative None
Permeabilization No
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提交于 Mar 29 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"