概述

  • 产品名称Anti-SLCO4C1抗体
  • 描述
    兔多克隆抗体to SLCO4C1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 523-553 of Human SLCO4C1 (NP_851322.3).

  • 阳性对照
    • NCI-H460 cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab111526 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 79 kDa.

靶标

  • 功能Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion-transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.
  • 组织特异性Predominantly expressed in kidney but also weakly expressed in both fetal liver and kidney.
  • 序列相似性Belongs to the organo anion transporter (TC 2.A.60) family.
    Contains 1 Kazal-like domain.
  • 细胞定位Basolateral cell membrane. Detected at the basolateral membrane of the proximal tubule cell in the kidney.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 9530051F04 antibody
    • C330017E21Rik antibody
    • OATP-H antibody
    • OATP-M1 antibody
    • Oatp4c1 antibody
    • OATPX antibody
    • Organic anion transporter M1 antibody
    • PRO2176 antibody
    • Slc21A20 antibody
    • SLCO4C1 antibody
    • SO4C1_HUMAN antibody
    • Solute carrier family 21 member 20 antibody
    • Solute carrier organic anion transporter family member 4C1 antibody
    see all

Anti-SLCO4C1 antibody 图像

  • Anti-SLCO4C1 antibody (ab111526) at 1/100 dilution + NCI-H460 cell line lysate at 35 µg

    Predicted band size : 79 kDa

Anti-SLCO4C1 antibody (ab111526)参考文献

ab111526 has not yet been referenced specifically in any publications.

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