概述

  • 产品名称Anti-SLC9A6抗体
    参阅全部 SLC9A6 一抗
  • 描述
    小鼠单克隆抗体to SLC9A6
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow
  • 免疫原

    Recombinant fragment: YGDSTVNTEP ATSSAPRRFM GNSSEDALDR ELAFGDHELV IRGTRLVLPM DDSEPPLNLL DNTRHGPA, corresponding to amino acids 602-669 of human SLC9A6 (NP_006350) with a 26 kDa tag

  • 阳性对照
    • SLC9A6 transfected 293T cell lysate; recombinant tagged fragment of human SLC9A6 (the immunogen).

性能

应用

Our Abpromise guarantee covers the use of ab77110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 74 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Electroneutral exchange of protons for Na(+) and K(+) across the early and recycling endosome membranes. Contributes to calcium homeostasis.
  • 组织特异性Ubiquitous; but is most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart.
  • 疾病相关Defects in SLC9A6 are the cause of mental retardation syndromic X-linked Christianson type (MRXSC) [MIM:300243]; also known as MRXS-Christianson or X-linked Angelman-like syndrome. The phenotype is characterized by profound mental retardation, epilepsy, ataxia, and microcephaly, and showed phenotypic overlap with Angelman syndrome.
  • 序列相似性Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • 细胞定位Endosome membrane. Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 3732426M05 antibody
    • 6430520C02Rik antibody
    • KIAA0267 antibody
    • mKIAA0267 antibody
    • MRSA antibody
    • Na(+)/H(+) exchanger 6 antibody
    • NHE-6 antibody
    • NHE6 antibody
    • OTTHUMP00000024089 antibody
    • OTTHUMP00000024090 antibody
    • RGD1563582 antibody
    • RP11-274K13.1 antibody
    • RP23-105E2.4 antibody
    • SL9A6_HUMAN antibody
    • SLC9A6 antibody
    • Sodium/hydrogen exchanger 6 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger), isoform 6 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger), member 6 antibody
    • Solute carrier family 9 member 6 antibody
    • solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 antibody
    see all

Anti-SLC9A6 antibody 图像

  • Anti-SLC9A6 antibody (ab77110) at 1/500 dilution + Recombinant fragment of human SLC9A6 at 0.2 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

    Predicted band size : 74 kDa
    Observed band size : 34 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-SLC9A6 antibody (ab77110) at 1/500 dilution

    Lane 1 : SLC9A6 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 74 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)

Anti-SLC9A6 antibody (ab77110)参考文献

ab77110 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab77110.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"