概述

  • 产品名称Anti-SLC7A7抗体
    参阅全部 SLC7A7 一抗
  • 描述
    小鼠多克隆抗体to SLC7A7
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human SLC7A7 protein (AAH03062.1)

  • 阳性对照
    • SLC7A7 transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab69872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 47 kDa (predicted molecular weight: 56 kDa).

靶标

  • 功能Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes.
  • 组织特异性Highest expression in kidney and peripheral blood leukocytes. Weaker expression is observed in lung, heart, placenta, spleen, testis and small intestine. Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, retinal pigment epithelial cells, and various carcinoma cell lines, with highest expression in a colon-carcinoma cell line.
  • 疾病相关Lysinuric protein intolerance
  • 序列相似性Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
  • 细胞定位Basolateral cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • LAT3 antibody
    • LPI antibody
    • Monocyte amino acid permease 2 antibody
    • MOP-2 antibody
    • MOP2 antibody
    • SLC7A 7 antibody
    • Slc7a7 antibody
    • Solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 antibody
    • Solute carrier family 7 member 7 antibody
    • y(+)L type amino acid transporter 1 antibody
    • y(+)L-type amino acid transporter 1 antibody
    • Y+L amino acid transporter 1 antibody
    • y+LAT-1 antibody
    • Y+LAT1 antibody
    • YLAT1_HUMAN antibody
    see all

Anti-SLC7A7 antibody 图像

  • All lanes : Anti-SLC7A7 antibody (ab69872) at 1/500 dilution

    Lane 1 : SLC7A7 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 56 kDa
    Observed band size : 47 kDa (why is the actual band size different from the predicted?)

Anti-SLC7A7 antibody (ab69872)参考文献

ab69872 has not yet been referenced specifically in any publications.

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