• 产品名称Anti-SLC7A5抗体
    参阅全部 SLC7A5 一抗
  • 描述
    山羊多克隆抗体to SLC7A5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog
  • 免疫原

    Synthetic peptide:


    , corresponding to internal sequence amino acids 419-432 of Human SLC7A5 (NP_003477.4).

  • 阳性对照
    • Human Spleen lysates.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab99419 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领���


Our Abpromise guarantee covers the use of ab99419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 55 kDa.


  • 功能Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.
  • 组织特异性Expressed abundantly in adult lung, liver, brain, skeletal muscle, placenta, bone marrow, testis, resting lymphocytes and monocytes, and in fetal liver. Weaker expression in thymus, cornea, retina, peripheral leukocytes, spleen, kidney, colon and lymph node. During gestation, expression in the placenta was significantly stronger at full-term than at the mid-trimester stage. Also expressed in all human tumor cell lines tested and in the astrocytic process of primary astrocytic gliomas. Expressed in retinal endothelial cells and in the intestinal epithelial cell line Caco-2.
  • 序列相似性Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
  • 细胞定位Cytoplasm > cytosol. Apical cell membrane. Located to the plasma membrane by SLC3A2/4F2hc. Localized to the apical membrane of placental syncytiophoblastic cells. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4F2 LC antibody
    • 4F2 light chain antibody
    • 4F2LC antibody
    • CD98 antibody
    • CD98 light chain antibody
    • CD98LC antibody
    • D16S469E antibody
    • DC49 antibody
    • E16 antibody
    • hLAT1 antibody
    • Integral membrane protein E16 antibody
    • L type amino acid transporter antibody
    • L type amino acid transporter 1 antibody
    • L-type amino acid transporter 1 antibody
    • Large neutral amino acids transporter 1 antibody
    • Large neutral amino acids transporter antibody
    • Large neutral amino acids transporter small subunit 1 antibody
    • LAT1 antibody
    • LAT1_HUMAN antibody
    • Membrane protein E16 antibody
    • MPE16 antibody
    • Slc7a5 antibody
    • Sodium independent neutral amino acid transporter antibody
    • Sodium independent neutral amino acid transporter LAT1 antibody
    • Solute carrier family 7 (cationic amino acid transporter y+ system) member 5 antibody
    • Solute carrier family 7 member 5 antibody
    • TA1 antibody
    • Tumor associated protein 1 antibody
    • y+ system cationic amino acid transporter antibody
    see all

Anti-SLC7A5 antibody 图像

  • All lanes : Anti-SLC7A5 antibody (ab99419) at 0.3 µg

    Lane 1 : Human Spleen lysate
    Lane 2 : Human Spleen lysate with immunizing peptide

    Lysates/proteins at 35 µg per lane.

    Predicted band size : 55 kDa

Anti-SLC7A5 antibody (ab99419)参考文献

ab99419 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 100000 cells
Gel Running Conditions Reduced Denaturing (10% gel)
Sample Mouse Cell lysate - whole cell (mouse embryonic stem cells)
Specification mouse embryonic stem cells
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 16°C

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提交于 Jan 08 2014