概述

  • 产品名称Anti-SLC6A8抗体
    参阅全部 SLC6A8 一抗
  • 描述
    兔多克隆抗体to SLC6A8
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    A region within synthetic peptide: CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSGGLEVPGA , corresponding to N terminal amino acids 181-230 of Human SLC6A8

  • 阳性对照
    • MDA MB 435S cell lysate, human muscle tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab62196 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 71, <36 kDa (predicted molecular weight: 71 kDa).Can be blocked with SLC6A8 peptide (ab216175). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

靶标

  • 功能Required for the uptake of creatine in muscles and brain.
  • 组织特异性Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
  • 疾病相关Cerebral creatine deficiency syndrome 1
  • 序列相似性Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • SLC6A 8 antibody
    • SLC6A8 antibody
    • Creatine transporter 1 antibody
    • Creatine transporter SLC6A8 antibody
    • CRT antibody
    • CRTR antibody
    • CT 1 antibody
    • CT1 antibody
    • MGC87396 antibody
    • SC6A8_HUMAN antibody
    • Slc6a8 antibody
    • Sodium and chloride-dependent creatine transporter 1 antibody
    • Sodium- and chloride-dependent creatine transporter 1 antibody
    • Solute carrier family 6 (neurotransmitter transporter, creatine), member 8. antibody
    • Solute carrier family 6 member 8 antibody
    see all

Anti-SLC6A8 antibody 图像

  • Anti-SLC6A8 antibody (ab62196) at 2.5 µg/ml + MDA MB 435S cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG 1/ 50,000 - 1/100,000 dilution

    Predicted band size : 71 kDa
    Observed band size : 71 kDa
    Additional bands at : <36 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human muscle tissue labelling SLC6A8 with ab62196 at 4-8µg/ml. Arrows indicate positively labelled skeletal muscle cells. Magnification: 400X.

Anti-SLC6A8 antibody (ab62196)参考文献

ab62196 has not yet been referenced specifically in any publications.

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