概述

  • 产品名称
  • 描述
    兔多克隆抗体to Slc6a6
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide: G PFLVRVKY LL TPREPNR WAV EREGAT PYNS RTVMN GALVK PTHI IVETMM , corresponding to amino acids 570-620 of Human Slc6a6

  • 阳性对照
    • Human lung carcinoma tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49.1% PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab111167 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆
    多克隆
  • 同种型
    IgG

应用

Our Abpromise guarantee covers the use of ab111167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    Required for the uptake of taurine. Transports both taurine and beta-alanine which requires sodium ions. Chloride ions are necessary for optimal uptake.
  • 组织特异性
    Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.
  • 序列相似性
    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
  • 翻译后修饰
    Down-regulated upon Ser-322 phosphorylation.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC10619 antibody
    • MGC131729 antibody
    • OTTHUMP00000208177 antibody
    • OTTHUMP00000208180 antibody
    • SC6A6_HUMAN antibody
    • SLC6A6 antibody
    • Sodium- and chloride-dependent taurine transporter antibody
    • Solute carrier family 6 (neurotransmitter transporter, taurine), member 6 antibody
    • Solute carrier family 6 member 6 antibody
    • TAUT antibody
    see all

图片

  • ab111167 at 1/50 dilution staining Slc6a6 in paraffin-embedded Human lung carcinoma tissue by Immunohistochemistry. The image on the right is treated with synthesized peptide.

文献

ab111167 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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