概述

  • 产品名称
    Anti-SLC5A11抗体
    参阅全部 SLC5A11 一抗
  • 描述
    兔多克隆抗体to SLC5A11
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from the extracellular domain of SLC5A11 (Human) conjugated to KLH

  • 阳性对照
    • Human brain cortex

性能

应用

Our Abpromise guarantee covers the use of ab61018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 功能
    Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.
  • 组织特异性
    Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes.
  • 序列相似性
    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 形式
    There are 4 isoforms produced by alternative splicing.
  • 别名
    • homolog of rabbit KST1 antibody
    • KST1 antibody
    • Na(+)/myo-inositol cotransporter 2 antibody
    • na+/myo-inositol cotransporter 2 antibody
    • putative sodium-coupled cotransporter RKST1 antibody
    • RKST1 antibody
    • SC5AB_HUMAN antibody
    • SGLT6 antibody
    • SLC5A11 antibody
    • SMIT2 antibody
    • Sodium-dependent glucose cotransporter antibody
    • Sodium/glucose cotransporter KST1 antibody
    • Sodium/myo-inositol cotransporter 2 antibody
    • Sodium/myo-inositol transporter 2 antibody
    • solute carrier family 5 (sodium/glucose cotransporter), member 11 antibody
    • Solute carrier family 5 member 11 antibody
    see all

图片

  • ab61018 at 10µg/ml staining formalin fixed paraffin embedded brain cortex tissue

文献

ab61018 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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