概述

  • 产品名称Anti-SLC4A8抗体
    参阅全部 SLC4A8 一抗
  • 描述
    小鼠单克隆抗体to SLC4A8
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: IEEISDLILD QQELSSDLND SMRVKVREAL LKKHHHQNEK KRNNLIPIVR SFAEVGKKQS DPHLMDKHGQ TVSPQSVPTT NLEVKNGVNC EHSPVDLSKV , corresponding to amino acids 187-287 of Human SLC4A8

性能

应用

Our Abpromise guarantee covers the use of ab56708 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
    • 组织特异性Expressed in the pyramidal cells of the hippocampus (at protein level). Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed in pancreas and kidney cortex.
    • 序列相似性Belongs to the anion exchanger (TC 2.A.31) family.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Electroneutral Na(+)-driven Cl-HCO3 exchanger antibody
      • Electroneutral sodium bicarbonate exchanger 1 antibody
      • k-NBC3 antibody
      • S4A8_HUMAN antibody
      • Slc4a8 antibody
      • SLC4A8 protein antibody
      • Solute carrier family 4 member 8 antibody
      see all

    Anti-SLC4A8 antibody 图像

    • SLC4A8 antibody (ab56708) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human salivary gland.
    • Western blot against tagged recombinant protein immunogen using ab56708 SLC4A8 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-SLC4A8 antibody (ab56708)参考文献

    ab56708 has not yet been referenced specifically in any publications.

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