概述

  • 产品名称
  • 描述
    兔多克隆抗体to SLC4A8
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 1-255 of the Human SLC4A8 protein (Q2Y0W8).

  • 阳性对照
    • IMR32 and U87-MG whole cell lysates.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.58% Tris, 20% Glycerol
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab125910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 117 kDa.

靶标

  • 功能
    Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
  • 组织特异性
    Expressed in the pyramidal cells of the hippocampus (at protein level). Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed in pancreas and kidney cortex.
  • 序列相似性
    Belongs to the anion exchanger (TC 2.A.31) family.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Electroneutral Na(+)-driven Cl-HCO3 exchanger antibody
    • Electroneutral sodium bicarbonate exchanger 1 antibody
    • k-NBC3 antibody
    • S4A8_HUMAN antibody
    • Slc4a8 antibody
    • SLC4A8 protein antibody
    • Solute carrier family 4 member 8 antibody
    see all

Anti-SLC4A8 antibody 图像

  • Anti-SLC4A8 antibody (ab125910) at 1/1000 dilution + Human U87-M6 whole cell lysate at 30 µg

    Predicted band size : 117 kDa

实验方案

Anti-SLC4A8 antibody (ab125910)参考文献

ab125910 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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