Anti-SLC4A8/NBC抗体(ab125910)
Key features and details
- Rabbit polyclonal to SLC4A8/NBC
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SLC4A8/NBC抗体 -
描述
兔多克隆抗体to SLC4A8/NBC -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant fragment within Human SLC4A8/NBC aa 1-255. The exact sequence is proprietary.
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阳性对照
- IMR32 and U87-MG whole cell lysates.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab125910于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 117 kDa.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 117 kDa. |
靶标
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功能
Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity. -
组织特异性
Expressed in the pyramidal cells of the hippocampus (at protein level). Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed in pancreas and kidney cortex. -
序列相似性
Belongs to the anion exchanger (TC 2.A.31) family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 9498 Human
- Entrez Gene: 59033 Mouse
- Entrez Gene: 315311 Rat
- Omim: 605024 Human
- SwissProt: Q2Y0W8 Human
- SwissProt: Q8TC60 Human
- SwissProt: Q8JZR6 Mouse
- SwissProt: Q6RVG2 Rat
see all -
别名
- Electroneutral Na(+)-driven Cl-HCO3 exchanger antibody
- Electroneutral sodium bicarbonate exchanger 1 antibody
- k-NBC3 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab125910 尚未被引用在任何文献中。