Anti-SLC4A5抗体(ab99131)

概述

  • 产品名称Anti-SLC4A5抗体
  • 描述
    兔多克隆抗体to SLC4A5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Drosophila melanogaster, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 899-948 (SIAHIDSLKM ETETSAPGEQ PQFLGVREQR VTGIIVFILT GISVFLAPIL) of Human SLC4A5 (NP_067019).

  • 阳性对照
    • THP-1 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab99131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 126 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry of 2:1. May have a housekeeping function in regulating the pH of tissues in which it is expressed. May play a role in mediating Na(+):HCO3(-) cotransport in hepatocytes and intrahepatic cholangiocytes. Also may be important in protecting the renal paranchyma from alterations in urine pH.
  • 组织特异性Highest expression observed in liver, spleen and testis; moderate expression in the choroid plexus, hippocampus, cerebrum and cerebellum of brain, and in kidney cortex and kidney medulla. Also observed in heart, pancreas, muscle, lung, placenta, stomach and small intestine. Weakest expression seen in peripheral blood lymphocytes, colon, duodenum, jejunum, ileum and skeletal muscle.
  • 序列相似性Belongs to the anion exchanger (TC 2.A.31) family.
  • 细胞定位Apical cell membrane. Expressed in the apical plasma membrane domain of a subset of collecting ducts in the renal medulla.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Electrogenic sodium bicarbonate cotransporter 4 antibody
    • MGC129662 antibody
    • NBC4 antibody
    • NBCe2 antibody
    • S4A5_HUMAN antibody
    • SLC4A5 antibody
    • Solute carrier family 4 member 5 antibody
    • Solute carrier family 4 sodium bicarbonate cotransporter member 5 antibody
    see all

Anti-SLC4A5 antibody 图像

  • Anti-SLC4A5 antibody (ab99131) at 1 µg/ml + THP-1 cell lysate at 10 µg

    Predicted band size : 126 kDa

Anti-SLC4A5 antibody (ab99131)参考文献

ab99131 has not yet been referenced specifically in any publications.

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