概述

  • 产品名称
    Anti-SLC39A6抗体
    参阅全部 SLC39A6 一抗
  • 描述
    兔多克隆抗体to SLC39A6
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide: RSCLIHTSEK KAEIPPKTYS LQIAWVGGFI AISIISFLSL LGVILVPLMN , corresponding to amino acids 301-350 of Human SLC39A6

  • 阳性对照
    • Jurkat cell lysate and human kidney tissue.

性能

应用

Our Abpromise guarantee covers the use of ab61307 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

靶标

  • 功能
    May act as a zinc-influx transporter.
  • 组织特异性
    Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma.
  • 序列相似性
    Belongs to the ZIP transporter (TC 2.A.5) family.
  • 翻译后修饰
    N-glycosylated.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Estrogen regulated protein LIV 1 6 antibody
    • Estrogen-regulated protein LIV-1 antibody
    • LIV 1 antibody
    • LIV 1 protein, estrogen regulated antibody
    • S39A6_HUMAN antibody
    • SLC39A6 antibody
    • Solute carrier family 39 (metal ion transporter), member 6 antibody
    • solute carrier family 39 (zinc transporter), member 6 antibody
    • Solute carrier family 39 member 6 antibody
    • Zinc transporter ZIP6 antibody
    • ZIP 6 antibody
    • ZIP-6 antibody
    • Zrt and Irt like protein 6 antibody
    • Zrt- and Irt-like protein 6 antibody
    see all

图片

  • Anti-SLC39A6 antibody (ab61307) at 1.25 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit Ig at 1/50000 dilution

    Predicted band size : 48 kDa
    Observed band size : 48 kDa
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling SLC39A6 with ab61307 at 4-8µg/ml. Arrows indicate positively labelled epithelial cells of the renal tubule. Magnification: 400X.

文献

This product has been referenced in:
  • Mendiola M  et al. Predictive value of angiogenesis-related gene profiling in patients with HER2-negative metastatic breast cancer treated with bevacizumab and weekly paclitaxel. Oncotarget 7:24217-27 (2016). IHC . Read more (PubMed: 26992213) »
  • Trokovic N  et al. Exosomal secretion of death bullets: a new way of apoptotic escape? Am J Physiol Endocrinol Metab 303:E1015-24 (2012). IHC-P ; Mouse . Read more (PubMed: 22912365) »

See all 2 Publications for this product

客户评价及客户问答

Thank you for your enquiry. The exact protocol used is as below: 1. Deparaffinize sections in 3 changes of xylene, 5 minutes each 2. Hydrate in 2 changes of 100% ethanol for 3 minutes each, 95% and 80% ethanol for 1 minute eac...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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