Anti-SLC39A5抗体(ab76191)

概述

  • 产品名称Anti-SLC39A5抗体
    参阅全部 SLC39A5 一抗
  • 描述
    兔多克隆抗体to SLC39A5
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region of Human SLC39A5

  • 阳性对照
    • Placenta lysate.

性能

应用

Our Abpromise guarantee covers the use of ab76191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Seems to play a central role in controlling organismal zinc status.
  • 组织特异性Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
  • 疾病相关Myopia 24, autosomal dominant
  • 序列相似性Belongs to the ZIP transporter (TC 2.A.5) family.
  • 翻译后修饰Glycosylated.
  • 细胞定位Basolateral cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • LZT Hs7 antibody
    • MGC34778 antibody
    • OTTHUMP00000211153 antibody
    • OTTHUMP00000211154 antibody
    • S39A5_HUMAN antibody
    • SLC39A5 antibody
    • solute carrier family 39 (metal ion transporter), member 5 antibody
    • Solute carrier family 39 member 5 antibody
    • Zinc transporter ZIP5 [Precursor] antibody
    • Zinc transporter ZIP5 antibody
    • ZIP 5 antibody
    • ZIP-5 antibody
    • ZIP5 antibody
    • Zrt and Irt like protein 5 antibody
    • Zrt- and Irt-like protein 5 antibody
    see all

Anti-SLC39A5 antibody 图像

  • Anti-SLC39A5 antibody (ab76191) at 1 µg/ml (in 5% skim milk / PBS buffer) + Placenta lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 57 kDa
    Observed band size : 57 kDa
  • ab76191 at 5 µg/ml staining SLC39A5 in Human small intestine by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections.
  • ab76191 at 5 µg/ml staining SLC39A5 in Human pancreas by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections.

Anti-SLC39A5 antibody (ab76191)参考文献

ab76191 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 20 µg
Gel Running Conditions Reduced Denaturing (8-16 % gradient)
Sample Mouse Tissue lysate - whole (colon)
Specification colon
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

卓弥 鈴木

Verified customer

提交于 May 16 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"