概述

  • 产品名称Anti-SLC39A5抗体
    参阅全部 SLC39A5 一抗
  • 描述
    小鼠多克隆抗体to SLC39A5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human SLC39A5 protein (NP_775867).

  • 阳性对照
    • SLC39A5 transfected 293T lysate.

性能

应用

Our Abpromise guarantee covers the use of ab69363 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 74 kDa (predicted molecular weight: 57 kDa).

靶标

  • 功能May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Seems to play a central role in controlling organismal zinc status.
  • 组织特异性Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
  • 疾病相关Myopia 24, autosomal dominant
  • 序列相似性Belongs to the ZIP transporter (TC 2.A.5) family.
  • 翻译后修饰Glycosylated.
  • 细胞定位Basolateral cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • LZT Hs7 antibody
    • MGC34778 antibody
    • OTTHUMP00000211153 antibody
    • OTTHUMP00000211154 antibody
    • S39A5_HUMAN antibody
    • SLC39A5 antibody
    • solute carrier family 39 (metal ion transporter), member 5 antibody
    • Solute carrier family 39 member 5 antibody
    • Zinc transporter ZIP5 [Precursor] antibody
    • Zinc transporter ZIP5 antibody
    • ZIP 5 antibody
    • ZIP-5 antibody
    • ZIP5 antibody
    • Zrt and Irt like protein 5 antibody
    • Zrt- and Irt-like protein 5 antibody
    see all

Anti-SLC39A5 antibody 图像

  • All lanes : Anti-SLC39A5 antibody (ab69363) at 1/500 dilution

    Lane 1 : SLC39A5 transfected 293T lysate
    Lane 2 : Non transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 57 kDa
    Observed band size : 74 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 76 kDa. We are unsure as to the identity of these extra bands.

Anti-SLC39A5 antibody (ab69363)参考文献

ab69363 has not yet been referenced specifically in any publications.

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