The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 74 kDa (predicted molecular weight: 57 kDa).
功能May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Seems to play a central role in controlling organismal zinc status.
组织特异性Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
疾病相关Myopia 24, autosomal dominant
序列相似性Belongs to the ZIP transporter (TC 2.A.5) family.