概述

  • 产品名称Anti-SLC39A13抗体
    参阅全部 SLC39A13 一抗
  • 描述
    兔多克隆抗体to SLC39A13
  • 特异性At least two isoforms of SLC39A13 are known to exist; ab106586 will detect both isoforms. ab106586 is predicted to not crossreact with other ZIP family members.
  • 经测试应用适用于: ICC/IF, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A 14 amino acid peptide near the amino terminus of Human SLC39A13 (NP_001121697).

  • 阳性对照
    • K562 cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab106586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Acts as a zinc-influx transporter.
  • 疾病相关Defects in SLC39A13 are the cause of Ehlers-Danlos syndrome-like spondylocheirodysplasia (SCD-EDS) [MIM:612350]. SCD-EDS is a 'spondylocheiro dysplastic form of Ehlers-Danlos syndrome'. The syndrome consists of a generalized skeletal dysplasia involving mainly the spine (spondylo) and striking clinical abnormalities of the hands (cheiro) in addition to the EDS-like features. Clinical features included postnatal growth retardation, moderate short stature, protuberant eyes with bluish sclerae, hands with finely wrinkled palms, atrophy of the thenar muscles, and tapering fingers. Patients have thin, hyperelastic skin and hypermobile small joints consistent with an Ehlers-Danlos-like phenotype. Radiologic features included mild to moderate platyspondyly, mild to moderate osteopenia of the spine, small ileum, flat proximal femoral epiphyses, short, wide femoral necks, and broad metaphyses (elbows, knees, wrists, and interphalangeal joints).
  • 序列相似性Belongs to the ZIP transporter (TC 2.A.5) family.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 形式There are 2 isoforms produced by alternative splicing.
  • 别名
    • FLJ25785 antibody
    • LIV-1 subfamily of ZIP zinc transporter 9 antibody
    • LZT-Hs9 antibody
    • S39AD_HUMAN antibody
    • SLC39A13 antibody
    • solute carrier family 39 (metal ion transporter), member 13 antibody
    • solute carrier family 39 (zinc transporter), member 13 antibody
    • Solute carrier family 39 member 13 antibody
    • Zinc transporter ZIP13 antibody
    • ZIP-13 antibody
    • Zrt- and Irt-like protein 13 antibody
    see all

Anti-SLC39A13 antibody 图像

  • Immunofluorescence of SLC39A13 in Human spleen tissue with ab106586 at 20 ug/mL.
  • Immunohistochemistry of SLC39A13 in Human spleen tissue with ab106586 at 2.5 μg/mL.

  • Anti-SLC39A13 antibody (ab106586) at 1 µg/ml + K562 cell lysate at 15 µg

    Predicted band size : 39 kDa

Anti-SLC39A13 antibody (ab106586)参考文献

ab106586 has not yet been referenced specifically in any publications.

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