概述

  • 产品名称Anti-SLC33A1抗体
    参阅全部 SLC33A1 一抗
  • 描述
    兔多克隆抗体to SLC33A1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 215-264 (CNSVGQTAGY FLGNVLFLAL ESADFCNKYL RFQPQPRGIV TLSDFLFFWG) of human SLC33A1 (NP_004724).

  • 阳性对照
    • Human Placenta lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab83868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides.
  • 组织特异性Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. With strongest signals in pancreas.
  • 疾病相关Spastic paraplegia autosomal dominant 42 (SPG42) [MIM:612539]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. Note=The disease is caused by mutations affecting the gene represented in this entry.
    Congenital cataracts, hearing loss, and neurodegeneration (CCHLND) [MIM:614482]: An autosomal recessive disorder characterized by congenital cataracts, severe psychomotor retardation, and hearing loss associated with decreased serum ceruloplasmin and copper. Brain MRI shows cerebral and cerebellar atrophy and hypomyelination. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 序列相似性Belongs to the SLC33A transporter family.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACATN antibody
    • ACATN_HUMAN antibody
    • Acetyl CoA transporter antibody
    • Acetyl Coenzyme A transporter antibody
    • Acetyl coenzyme A transporter 1 antibody
    • Acetyl-CoA transporter 1 antibody
    • Acetyl-coenzyme A transporter 1 antibody
    • AT 1 antibody
    • AT-1 antibody
    • AT1 antibody
    • Human Angiotensin II Type 1 Receptor antibody
    • Slc33a1 antibody
    • Solute carrier family 33 (acetyl CoA transporter) member 1 antibody
    • Solute carrier family 33 member 1 antibody
    • spastic paraplegia 42 (autosomal dominant) antibody
    • SPG42 antibody
    see all

Anti-SLC33A1 antibody 图像

  • Anti-SLC33A1 antibody (ab83868) at 1 µg/ml (5% skim milk / PBS buffer) + Placenta lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 61 kDa
    Observed band size : 61 kDa

Anti-SLC33A1 antibody (ab83868)参考文献

ab83868 has not yet been referenced specifically in any publications.

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