概述

  • 产品名称Anti-SLC30A5抗体
  • 描述
    小鼠单克隆抗体to SLC30A5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-119 of Human SLC30A5

性能

应用

Our Abpromise guarantee covers the use of ab57590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP.
    • 组织特异性Ubiquitously expressed. Highly expressed in pancreas, liver and kidney. Expressed abundantly in insulin-containing beta cells, undetectable in other endocrine cell types including glucagon-secreting alpha cells and most acinar cells.
    • 序列相似性Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
    • 细胞定位Golgi apparatus > trans-Golgi network membrane. Perimeter of granules, localizes to the brush border membrane of the enterocyte. Concentrated in early compartments of the secretory pathway such as COPII-coated vesicles.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZp686F23142 antibody
      • FLJ12496 antibody
      • FLJ12756 antibody
      • hZTL1 antibody
      • MGC5499 antibody
      • Putative uncharacterized protein DKFZp686F23142 antibody
      • Slc30a5 antibody
      • Solute carrier family 30 (zinc transporter) member 5 antibody
      • Solute carrier family 30 (Zinc transporter), member 5 isoform CRA a antibody
      • Solute carrier family 30 member 5 antibody
      • Zinc transporter 5 antibody
      • Zinc transporter ZnT 5 antibody
      • Zinc transporter ZTL1 antibody
      • ZNT 5 antibody
      • ZnT-5 antibody
      • ZnT-like transporter 1 antibody
      • ZNT5 antibody
      • ZNT5_HUMAN antibody
      • ZNTL 1 antibody
      • ZNTL1 antibody
      • ZTL 1 antibody
      • ZTL1 antibody
      see all

    Anti-SLC30A5 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57590 SLC30A5 antibody at 1ug/ml. Predicted band size of immunogen is 39 kDa

    Anti-SLC30A5 antibody (ab57590)参考文献

    ab57590 has not yet been referenced specifically in any publications.

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