概述

  • 产品名称Anti-SLC25A3抗体
    参阅全部 SLC25A3 一抗
  • 描述
    小鼠多克隆抗体to SLC25A3
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human SLC25A3 protein (NP_002626.1)

  • 阳性对照
    • Human pancreas tissue lysate, SLC25A3 transfected 293T cell line lysate and HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab89117 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+).
  • 疾病相关Defects in SLC25A3 are a cause of mitochondrial phosphate carrier deficiency (MPCD) [MIM:610773]. MPCD is a fatal disorder of oxidative phosphorylation. Patients have lactic acidosis, hypertrophic cardiomyopathy and muscular hypotonia and die within the first year of life.
  • 序列相似性Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • 细胞定位Mitochondrion inner membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • mitochondrial antibody
    • Mitochondrial phosphate carrier protein antibody
    • MPCP_HUMAN antibody
    • OK/SW cl.48 antibody
    • PHC antibody
    • Phosphate carrier protein antibody
    • Phosphate carrier protein mitochondrial antibody
    • Phosphate carrier protein mitochondrial precursor antibody
    • Phosphate transport protein antibody
    • PTP antibody
    • Slc25a3 antibody
    • Solute carrier family 25 member 3 antibody
    • Solute carrier family 25 mitochondrial carrier phosphate carrier member 3 antibody
    see all

Anti-SLC25A3 antibody 图像

  • Anti-SLC25A3 antibody (ab89117) at 1 µg/ml + Human pancreas tissue lysate at 50 µg

    Predicted band size : 40 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-SLC25A3 antibody (ab89117) at 1 µg/ml

    Lane 1 : SLC25A3 transfected 293T cell line lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 40 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.
  • ab89117, at 10 µg/ml staining SLC25A3 in HeLa cells by Immunofluorescence.

Anti-SLC25A3 antibody (ab89117)参考文献

ab89117 has not yet been referenced specifically in any publications.

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