Anti-SLC25A3抗体(ab67121)

概述

  • 产品名称Anti-SLC25A3抗体
    参阅全部 SLC25A3 一抗
  • 描述
    小鼠多克隆抗体to SLC25A3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length SLC25A3 protein (Human)

  • 阳性对照
    • 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab67121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/1000. Detects bands of approximately 34 and 40 kDa (predicted molecular weight: 40 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+).
    • 疾病相关Defects in SLC25A3 are a cause of mitochondrial phosphate carrier deficiency (MPCD) [MIM:610773]. MPCD is a fatal disorder of oxidative phosphorylation. Patients have lactic acidosis, hypertrophic cardiomyopathy and muscular hypotonia and die within the first year of life.
    • 序列相似性Belongs to the mitochondrial carrier family.
      Contains 3 Solcar repeats.
    • 细胞定位Mitochondrion inner membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • mitochondrial antibody
      • Mitochondrial phosphate carrier protein antibody
      • MPCP_HUMAN antibody
      • OK/SW cl.48 antibody
      • PHC antibody
      • Phosphate carrier protein antibody
      • Phosphate carrier protein mitochondrial antibody
      • Phosphate carrier protein mitochondrial precursor antibody
      • Phosphate transport protein antibody
      • PTP antibody
      • Slc25a3 antibody
      • Solute carrier family 25 member 3 antibody
      • Solute carrier family 25 mitochondrial carrier phosphate carrier member 3 antibody
      see all

    Anti-SLC25A3 antibody 图像

    • All lanes : Anti-SLC25A3 antibody (ab67121) at 1/500 dilution

      Lane 1 : SLC25A3 transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 25 µg/ml per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 40 kDa
      Observed band size : 40 kDa
      Additional bands at : 34 kDa. We are unsure as to the identity of these extra bands.

    Anti-SLC25A3 antibody (ab67121)参考文献

    ab67121 has not yet been referenced specifically in any publications.

    Product Wall

    Application Western blot
    Sample Rat Tissue lysate - other (brain cortex mitochondria)
    Loading amount 50 µg
    Specification brain cortex mitochondria
    Gel Running Conditions Reduced Denaturing (SDS-PAGE 12%)
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
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    提交于 Oct 22 2009

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"