概述

  • 产品名称Anti-SLC25A12抗体
    参阅全部 SLC25A12 一抗
  • 描述
    兔多克隆抗体to SLC25A12
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of the Human SLC25A12 protein (O75746).

  • 阳性对照
    • Human prostate carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab111415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Calcium-dependent mitochondrial aspartate and glutamate carrier. May have a function in the urea cycle.
  • 组织特异性High levels in heart and skeletal muscle, low in brain and very low in kidney.
  • 疾病相关Defects in SLC25A12 are the cause of aspartate-glutamate carrier 1 deficiency (AGC1D) [MIM:612949]; also called global cerebral hypomyelination. This syndrome consists of a child severe psychomotor retardation, hypotonia and hypomyelination of the central nervous system.
  • 序列相似性Belongs to the mitochondrial carrier family.
    Contains 4 EF-hand domains.
    Contains 3 Solcar repeats.
  • 细胞定位Mitochondrion inner membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AGC1 antibody
    • Araceli hiperlarga antibody
    • ARALAR antibody
    • ARALAR1 antibody
    • Calcium binding mitochondrial carrier superfamily member antibody
    • Calcium binding mitochondrial carrier superfamily member Aralar1 antibody
    • Calcium-binding mitochondrial carrier protein Aralar1 antibody
    • CMC1_HUMAN antibody
    • Mitochondrial aspartate glutamate carrier 1 antibody
    • SLC25A12 antibody
    • Solute carrier family 25 (aspartate/glutamate carrier) member 12 antibody
    • Solute carrier family 25 (mitochondrial carrier Aralar) member 12 antibody
    • Solute carrier family 25 member 12 antibody
    • solute carrier family 25, member 12 antibody
    see all

Anti-SLC25A12 antibody 图像

  • Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using SLC25A12 Antibody (ab111415). The picture on the right is treated with the synthesized peptide.

Anti-SLC25A12 antibody (ab111415)参考文献

ab111415 has not yet been referenced specifically in any publications.

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